Tumor Necrosis Factor-α, Uterine Natural Killer Cells, and Pregnancy
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چکیده
منابع مشابه
Role of Tumor Necrosis Factor-α and Natural Killer Cells in Uterine Artery Function and Pregnancy Outcome in the Stroke-Prone Spontaneously Hypertensive Rat
Women with chronic hypertension are at increased risk of maternal and fetal morbidity and mortality. We have previously characterized the stroke-prone spontaneously hypertensive rat (SHRSP) as a model of deficient uterine artery function and adverse pregnancy outcome compared with the control Wistar-Kyoto. The activation of the immune system plays a role in hypertension and adverse pregnancy ou...
متن کاملTumor necrosis factor-like weak inducer of apoptosis regulates the phenotype and cytotoxic activity of goat uterine natural killer cells.
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) has an important role in the promotion of cell proliferation, migration, and differentiation. However, very little is known about the role of TWEAK in modulating uterine natural killer (uNK) cells' comprehensive functions in ruminants. In the present study, the effects of TWEAK on goat uNK cells were investigated by measuring their cy...
متن کامل[Anti-tumor necrosis factor-α medications and pregnancy].
En los últimos años se han desarrollado medicamentos que inhiben el TNF-a, porque esta citocina tiene un efecto inflamatorio que condiciona el proceso patológico de diversas enfermedades autoinmunitarias sistémicas, como artritis reumatoide, psoriasis, enfermedades inflamatorias intestinales y otras. Actualmente existen en el mercado farmacéutico 5 fármacos que inhiben el TNF-a: 3 anticuerpos m...
متن کاملTumor Necrosis Factor-α and Pregnancy Complications: A Prospective Study
OBJECTIVE The aim of this study was to compare the levels of tumor necrosis factor-α (TNF-α) produced by peripheral blood mononuclear cells in normal pregnancies and pregnancies with complications. MATERIALS AND METHODS Maternal peripheral blood mononuclear cells from women with a recurrent spontaneous miscarriage (n = 35), premature rupture of fetal membranes (n = 30), preeclampsia (n = 27) ...
متن کاملThe Effect of Ethanolic Extract of Salvia officinalis on the Uterine Natural Killer Cells Population at Day 7 of Pregnancy
Background: Pregnancy is one of the changer agents for defensive cells, however it is unknown the effect of the ethanolic extract of the Salvia officinalis on the uterine Natural Killer cells population in the pregnant mice that needs to be investigated. Objective: The aim of this study was to determine the effect of the ethanolic extract of the Salvia officinalis on the uterine Natural Kill...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2016
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.116.08028